insulin receptor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1259	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor 1142-1153,Insulin Receptor 1142-1153
	[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153) functions as a substrate for insulin receptor tyrosine kinase. This substance effectively binds to insulin and exhibits the potential for utilization in scientif...
T8221	Insulin (human)	INSULIN,Insulin(human)	IGF-1R
	Insulin (human) is a peptide hormone that promotes glycogen synthesis and regulates glucose levels in the blood. Insulin (human) has hypoglycemic activity and is used clinically to treat hyperglycemia in diabetic patient...		IGF-1R
TP1125	Insulin(cattle)	Insulin from bovine pancreas	IGF-1R
	Insulin bovine (Insulin from bovine pancreas) is a biologically derived two-chain polypeptide hormone, synthesized in vivo by pancreatic β cells. It is frequently utilized as a growth supplement in cell culture applicati...		IGF-1R
T8348	Phentolamine		Adrenergic Receptor
	Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist		Adrenergic Receptor
T8773	MID-1		Others , IGF-1R
	MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction. It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skelet...		Others , IGF-1R
T9030	SU4984		FGFR , IGF-1R , PDGFR
	SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).		FGFR , IGF-1R , PDGFR
T21761	HNMPA		IGF-1R
	HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote...		IGF-1R
T6003	GSK1904529A	GSK 4529	Apoptosis , Raf , VEGFR , IGF-1R , Syk
	GSK1904529A (GSK 4529) is a specific inhibitor of IGF-1R (IC50=27 nM) and IR(IC50=25 nM) .		Apoptosis , Raf , VEGFR , IGF-1R , Syk
T2349	BMS-754807		Trk receptor , c-Met/HGFR , IGF-1R
	Dual IGF-1R/InsR Inhibitor BMS-754807 is an oral small molecule inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (InsR) tyrosine kinases with potential antineoplastic activity.		Trk receptor , c-Met/HGFR , IGF-1R
T10539	BIBO3304 TFA		Neuropeptide Y Receptor
	BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).		Neuropeptide Y Receptor
T3079	GSK1838705A		IGF-1R , JNK , S6 Kinase , ALK
	GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases.		IGF-1R , JNK , S6 Kinase , ALK
TQ0020	AMG 837 calcium hydrate		GPR
	AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).		GPR
T9609	GRK5-IN-2		GRK
	GRK5-IN-2, a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor. It regulates the expression and/or release of insulin and is useful for the metabolic disease research.		GRK
T6017	Linsitinib	OSI-906	IGF-1R
	OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, whic...		IGF-1R
T8329	AR 231453		GPR
	AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.		GPR
T7127	DC260126		Apoptosis , GPR
	DC260126 is a small-molecule antagonist of FFA1 (GPR40)		Apoptosis , GPR
T2607	MSDC 0160	CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others , IGF-1R , Mitochondrial Metabolism
	MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.		Others , IGF-1R , Mitochondrial Metabolism
T21623	AS1269574	AS 1269574	GPR , TRP/TRPV Channel
	AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.		GPR , TRP/TRPV Channel
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T1791	Ceritinib	LDK378	Serine Protease , IGF-1R , ALK
	Ceritinib (LDK378) is a specific ALK inhibitor (IC50: 0.2 nM).		Serine Protease , IGF-1R , ALK